Neuroscience Resource Guide: Data Sources

"As part of a 10-year plan launched in March 2012 to understand the neural code—how activity in the brain's cortex leads to perception, decision making, and ultimately action—the Allen Institute has created a set of large-scale programs to understand the fundamentals of the cortex. We will be focusing our understanding through simultaneous study of the brain's components, computation and cognition."

Cell and molecular biology news, books, tools and resources.

An interactive brain atlas based on over 20 million megapixels of sub-micron resolution, annotated, scanned images of serial sections of both primate & non-primate brains. Images are searchable.

Provides images of and information about well-preserved, sectioned and stained brains of mammals. Viewers can see and download photographs of brains of over 100 different species of mammals. Also available are examples of stained sections of mammalian brains.

EMBL-EBI, Databases of biological data including nucleic acid, protein sequences and macromolecular structures.

Cross-database search page that includes: PubMed, OMIM, OMIA, PubChem, Nucleotide, Protein, Genome, Structure, singlenucleotide polymorphism, UniGene, conserved protein domain databases, UniSTS, Cancer Chromosomes, Genome Project, and more.

Expert Protein Analysis System (ExPASy) provides access to scientific databases & software tools in different areas of life sciences, including proteomics, genomics, phylogeny, systems biology, & more.

Free Genome Sciences images from the Department of Energy Human Genome Project.
"Almost all the images on these pages are original graphics created by the U.S. Department of Energy Genomic Science program's Biological and Environmental Research Information System (BERIS)."

Provides a way to learn about basic neuroscience research procedures & tools by dissecting, observing, & collecting neurophysiological data from a leech.

Demonstrate 3-D animation of molecules; free software may be downloaded.

from University of Southern California, the LONI Image Data Archive (IDA) is a user-friendly environment for archiving, searching, sharing, tracking and disseminating neuroimaging and related clinical data.

"The Common Fund’s Molecular Libraries and Imaging program offered biomedical researchers access to the large-scale screening capacity necessary to identify small molecules that could be optimized as chemical probes to study the functions of genes, cells, and biochemical pathways in health and disease. They are also used by researchers in the public and private sectors to validate new drug targets, which could then move into the drug-development pipeline."

Includes GenBank, Entrez, Cancer Genome Database, Human Genome Database, & more.

Takes a DNA sequence & finds large, non-overlapping open reading frames using the E.coli genetic code & the sites for all Type II & commercially available Type III restriction enzymes that cut the sequence just once.

Provides a dynamically searchable database of 3 types of neuronal properties: voltage gated conductances, neurotransmitter receptors, and neurotransmitter substances.

Worldwide repository for the processing and distribution of 3-D biological macromolecular structure data.

Provides information on the biological activities of small molecules. Part of NIH's Molecular Libraries Roadmap Initiative.

Contains related databases that support experimental & theoretical research on the membrane properties that mediate information processing in nerve cells, using the olfactory pathway as a model system.

"BrainFacts.org is an authoritative source of information about the brain and nervous system for the public."

Provides information on the structural basis of synaptic function. Includes an atlas of ultrastructual neurocytology, images of brain structures & cells ), tutorials, & a suite of tools for the analysis & 3-D reconstruction of structures from serial sections.

Contains links to many websites of interest to neuroscientists.

An introduction to basic neuroanatomy, with emphasis on the pathoanatomy of several leading central nervous system diseases.